by M. F. Maitz, R. Gago, B. Abendroth, M. Camero, I. Caretti and U. Kreissig
Abstract:
Mechanical heart valves are exposed to extreme mechanical demands, which require a surface showing not only nonhaemostatic properties, but also wear resistance and low friction. As alternative to different forms of amorphous carbon (a-C), so-called diamond-like carbon (DLC), the suitability of boron carbonitride (BCN) coatings is tested here for hemocompatible coatings. They have similar mechanical properties like a-C surfaces, but superior chemical stability at ferrous substrates or counterparts. BCN films with different nitrogen content were compared with hydrogenated a-C films regarding their mechanical properties, surface energy, adsorption of albumin and fibrinogen, blood platelet adherence, and activation of the contact system of the clotting cascade and kinin system. Similar mechanical properties and biological response have been found in the BCN films with respect to a-C, indicating the potential of these coatings for biomedical applications. The increase in the crystallinity and tribological properties of the BCN samples with a higher incorporation of N was also followed by a lower protein adsorption and low activation of the contact system, but an increased adherence of thrombocytes. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006
Reference:
M. F. Maitz, R. Gago, B. Abendroth, M. Camero, I. Caretti and U. Kreissig, “Hemocompatibility of low-friction boron–carbon–nitrogen containing coatings”, Journal of Biomedical Materials Research Part B: Applied Biomaterials, vol. 77B, no. 1, pp. 179–187.
Bibtex Entry:
@article{maitz_hemocompatibility_2006,
	title = {Hemocompatibility of low-friction boron–carbon–nitrogen containing coatings},
	volume = {77B},
	issn = {1552-4981},
	url = {http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.30435/abstract},
	doi = {10.1002/jbm.b.30435},
	abstract = {Mechanical heart valves are exposed to extreme mechanical demands, which require a surface showing not only nonhaemostatic properties, but also wear resistance and low friction. As alternative to different forms of amorphous carbon (a-C), so-called diamond-like carbon (DLC), the suitability of boron carbonitride (BCN) coatings is tested here for hemocompatible coatings. They have similar mechanical properties like a-C surfaces, but superior chemical stability at ferrous substrates or counterparts. BCN films with different nitrogen content were compared with hydrogenated a-C films regarding their mechanical properties, surface energy, adsorption of albumin and fibrinogen, blood platelet adherence, and activation of the contact system of the clotting cascade and kinin system. Similar mechanical properties and biological response have been found in the BCN films with respect to a-C, indicating the potential of these coatings for biomedical applications. The increase in the crystallinity and tribological properties of the BCN samples with a higher incorporation of N was also followed by a lower protein adsorption and low activation of the contact system, but an increased adherence of thrombocytes. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006},
	language = {en},
	number = {1},
	urldate = {2017-07-21},
	journal = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
	author = {Maitz, M. F. and Gago, R. and Abendroth, B. and Camero, M. and Caretti, I. and Kreissig, U.},
	month = apr,
	year = {2006},
	keywords = {amorphous carbon, boron carbonitride, diamond-like carbon, hemocompatibility, tribology},
	pages = {179--187},
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}