by Alvaro Muñoz Noval, Vanessa Sánchez Vaquero, Esther Punzón Quijorna, Vicente Torres Costa, Darío Gallach Pérez, Laura González Méndez, Isabel Montero, Raul J. Martín Palma, Aurelio Climent Font, Josefa P. García Ruiz and Miguel Manso Silván
Abstract:
The surface properties of porous silicon (PSi) evolve rapidly in phosphate-buffered saline. X-ray photoelectron spectra indicate the formation of a Si–OH and C–O enriched surface, which becomes increasingly hydrophilic with aging time. Multiscale stripe micropatterns of Si and PSi have been fabricated by means of a high-energy ion-beam irradiation process. These micropatterns have been aged in physiological conditions and used to analyze human mesenchymal stem cell (hMSC) adhesion. The actin cytoskeleton of hMSCs orients following the uniaxial micropatterns. In the wider Si stripes, hMSCs are dominantly located on Si areas. However, for reduced Si widths, adhesion is avoided on PSi by a split assembly of the actin cytoskeleton on two parallel Si areas. These results confirm that nanostructured Si–OH/C–O-rich surfaces with hydrophilic character are specially adapted for the creation of cell adhesion surface contrasts. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2012.
Reference:
Alvaro Muñoz Noval, Vanessa Sánchez Vaquero, Esther Punzón Quijorna, Vicente Torres Costa, Darío Gallach Pérez, Laura González Méndez, Isabel Montero, Raul J. Martín Palma, Aurelio Climent Font, Josefa P. García Ruiz and Miguel Manso Silván, “Aging of porous silicon in physiological conditions: Cell adhesion modes on scaled 1D micropatterns”, Journal of Biomedical Materials Research Part A, vol. 100A, no. 6, pp. 1615–1622.
Bibtex Entry:
@article{noval_aging_2012,
title = {Aging of porous silicon in physiological conditions: {Cell} adhesion modes on scaled {1D} micropatterns},
volume = {100A},
issn = {1552-4965},
shorttitle = {Aging of porous silicon in physiological conditions},
url = {http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34108/abstract},
doi = {10.1002/jbm.a.34108},
abstract = {The surface properties of porous silicon (PSi) evolve rapidly in phosphate-buffered saline. X-ray photoelectron spectra indicate the formation of a Si–OH and C–O enriched surface, which becomes increasingly hydrophilic with aging time. Multiscale stripe micropatterns of Si and PSi have been fabricated by means of a high-energy ion-beam irradiation process. These micropatterns have been aged in physiological conditions and used to analyze human mesenchymal stem cell (hMSC) adhesion. The actin cytoskeleton of hMSCs orients following the uniaxial micropatterns. In the wider Si stripes, hMSCs are dominantly located on Si areas. However, for reduced Si widths, adhesion is avoided on PSi by a split assembly of the actin cytoskeleton on two parallel Si areas. These results confirm that nanostructured Si–OH/C–O-rich surfaces with hydrophilic character are specially adapted for the creation of cell adhesion surface contrasts. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2012.},
language = {en},
number = {6},
urldate = {2017-10-10},
journal = {Journal of Biomedical Materials Research Part A},
author = {Noval, Alvaro Muñoz and Vaquero, Vanessa Sánchez and Quijorna, Esther Punzón and Costa, Vicente Torres and Pérez, Darío Gallach and Méndez, Laura González and Montero, Isabel and Palma, Raul J. Martín and Font, Aurelio Climent and Ruiz, Josefa P. García and Silván, Miguel Manso},
month = jun,
year = {2012},
keywords = {cell guides, ion-beam modification, mesenchymal stem cells, physiological aging, porous silicon},
pages = {1615--1622},
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}